Hydrochloric Acid → 2-[2-[1-(6-Methyl-pyrimidin-4-yl)-piperidin-4-ylamino]-6-(4-trifluoromethyl-phenyl)-pyrimidin-4-yl]-propan-2-ol
Reaction equation
[CH3:3][c:4]1[cH:5][c:6]([N:10]2[CH2:11][CH2:12][CH:13]([NH2:16])[CH2:14][CH2:15]2)[n:7][cH:8][n:9]1.[CH3:47][N:48]1[CH2:49][CH2:50][CH2:51][C:52]1=[O:53].[CH:38]([N:39]([CH2:40][CH3:41])[CH:42]([CH3:43])[CH3:44])([CH3:45])[CH3:46].[Cl:17][c:18]1[n:19][c:20](-[c:28]2[cH:29][cH:30][c:31]([C:34]([F:35])([F:36])[F:37])[cH:32][cH:33]2)[cH:21][c:22]([C:24]([CH3:25])([CH3:26])[OH:27])[n:23]1.[ClH:1].[ClH:2].[OH2:54]>>[CH3:3][c:4]1[cH:5][c:6]([N:10]2[CH2:11][CH2:12][CH:13]([NH:16][c:18]3[n:19][c:20](-[c:28]4[cH:29][cH:30][c:31]([C:34]([F:35])([F:36])[F:37])[cH:32][cH:33]4)[cH:21][c:22]([C:24]([CH3:25])([CH3:26])[OH:27])[n:23]3)[CH2:14][CH2:15]2)[n:7][cH:8][n:9]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-54068888d69f417ea51e8da35ddd737b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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