2-Chlorophenol → Ethyl 3-phenoxyprop-2-enoate

HRID 2049834Notes

Reaction equation

HRID 2049834 reaction equation
[C:1]([O:5][CH2:6][CH3:7])(=[O:4])[C:2]#[CH:3].Cl[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[OH:15].C(N(CC)CC)C>C(OCC)C>[O:15]([CH:3]=[CH:2][C:1]([O:5][CH2:6][CH3:7])=[O:4])[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:9]=1

Participants

5

Reactant 3

HCID 72452-ChlorophenolHCID 8471TriethylamineHCID 12182Ethyl propiolate

Product 1

HCID 237844Ethyl 3-phenoxyprop-2-enoate

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 5.77 mmol of ethyl propiolate in 20 ml ethyl ether is treated with 5.77 mmol 2-chlorophenol and 0.4 ml triethylamine (added slowly and with stirring). The reaction mixture is stirred overnight at RT, after which the solvent is removed under vacuum to yield ethyl 3-phenoxy-2-propenoate.

Workup

  1. additionadded slowly
  2. stirringThe reaction mixture is stirred overnight at RT
  3. customafter which the solvent is removed under vacuum

Sources & evidence

ORD record
ord-975a1ad880cd4c5ca6ac7376a489e99a
Source dataset
uspto-grants-1980_04
Patent number
US04198527

Reaction notes

Loading…