Triethylamine → HCID 23452884, compound

HRID 2049914Notes

Reaction equation

HRID 2049914 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([CH:13]=[C:14]([C:19]([O:21][CH3:22])=[O:20])[C:15]=1[N+:16]([O-:18])=[O:17])[O:8][CH2:9][C:10](Cl)=[O:11])([O:3][CH3:4])=[O:2].[CH2:23]([NH:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].C(N(CC)CC)C>O1CCCC1>[C:1]([C:5]1[CH:6]=[C:7]([CH:13]=[C:14]([C:19]([O:21][CH3:22])=[O:20])[C:15]=1[N+:16]([O-:18])=[O:17])[O:8][CH2:9][C:10]([N:29]([CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])=[O:11])([O:3][CH3:4])=[O:2]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 8920DihexylamineHCID 23452885HCID 23452885, compound

Product 1

HCID 23452884HCID 23452884, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

A stirred solution of (3,5-dicarbomethoxy-4-nitrophenoxy)acetyl chloride in tetrahydrofuran, cooled in an ice bath, is treated dropwise with a tetrahydrofuran solution containing 1 equivalent each of dihexylamine and triethylamine. After the addition, the precipitated amino hydrochloride is removed by filtration and the tetrahydrofuran filtrate is concentrated under reduced pressure to an oil which is used directly in the next step.

Workup

  1. additionAfter the addition
  2. customthe precipitated amino hydrochloride is removed by filtration
  3. concentrationthe tetrahydrofuran filtrate is concentrated under reduced pressure to an oil which

Sources & evidence

ORD record
ord-a437d95be65b4df6b60ef0c4c9ca3797
Source dataset
uspto-grants-1980_04
Patent number
US04199354

Reaction notes

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