1,1-Bis(methylthio)-2-nitroethylene → HCID 73677132, compound

HRID 2050146Notes

Reaction equation

HRID 2050146 reaction equation
O[CH2:2][C:3]1[S:4][CH:5]=[CH:6][N:7]=1.Cl.[SH:9][CH2:10][CH2:11][CH2:12][NH2:13].CS[C:16](SC)=[CH:17][N+:18]([O-:20])=[O:19].[CH2:23]([NH2:26])[C:24]#[CH:25]>Br>[N+:18]([CH:17]=[C:16]([NH:26][CH2:23][C:24]#[CH:25])[NH:13][CH2:12][CH2:11][CH2:10][S:9][CH2:2][C:3]1[S:4][CH:5]=[CH:6][N:7]=1)([O-:20])=[O:19]

Participants

6

Reactant 4

HCID 836231,1-Bis(methylthio)-2-nitroethyleneHCID 197870(3-Mercaptopropyl)ammonium chlorideHCID 239041PropargylamineHCID 27952131,3-Thiazol-2-ylmethanol

Product 1

HCID 73677132HCID 73677132, compound

Reagents, catalysts & solvents 1

HCID 260Hydrogen BromideSolvent

Procedure

When 2-hydroxymethylthiazole is reacted with 3-mercaptopropylamine hydrochloride [prepared according to the procedure described in J. Org. Chem., 27, 2846 (1962)] in aqueous hydrobromic acid (48%) and the resultant amine successively treated with 1,1-bis(methylthio)-2-nitroethylene and excess propargylamine, the title compound is produced.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-179bf7fcc3bd4cc29a30fe50b5ccb1ac
Source dataset
uspto-grants-1980_04
Patent number
US04200578

Reaction notes

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