Ammonia → HCID 15056980, compound

HRID 2050917Notes

Reaction equation

HRID 2050917 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]([NH:14][CH2:15][C:16]([O:18]C)=O)[C:7]([O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[O:8].[NH3:20].C>C(OCC)(=O)C>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]([NH:14][CH2:15][C:16]([NH2:20])=[O:18])[C:7]([O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[O:8]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 297MethaneHCID 19834269HCID 19834269, compound

Product 1

HCID 15056980HCID 15056980, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A mixture of 7.4 g of the compound from Example 3 and 50 ml of concentrated methanolic ammonia is left to stand at room temperature for 15 h. The solvent is stripped off, the residue is treated with active charcoal in hot ethyl acetate, and the mixture is filtered. The residue remaining after evaporation of the solvent is stirred with diethyl ether, filtered off with suction and dried.

Workup

  1. waitis left
  2. filtrationthe mixture is filtered
  3. customafter evaporation of the solvent
  4. filtrationfiltered off with suction
  5. customdried

Sources & evidence

ORD record
ord-358ea7017dae4e56a07cfb09ae9ba4a5
Source dataset
uspto-grants-1991_05
Patent number
US05015659

Reaction notes

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