反应详情

温度

50 °C

A mixture of 2-bromo-1-(naphthalen-2-yl)ethanone (0.95 g, 3.8 mmol), N-phenacyl piperazine dihydrochloride (0.89 g, 3.2 mmol) and K2CO3 (1.56 g, 11.2 mmol) in 30 ml of DMF was stirred at 50° C. for 10 h, and treated according to the general preparation 2 to give compound (IV-7), 0.88 g (60.69%), mp 236-237° C., M+ 373.

1. additiontreated
2. customaccording to the general preparation 2
3. customto give compound (IV-7), 0.88 g (60.69%), mp 236-237° C., M+ 373