huagongshe.com
HRID2052816

反应详情

EQUATION

反应方程式

HRID 2052816 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：O=S(=O)(Cl)Cc1ccc(F)cc1F
HCID2761455

(2,4-difluorophenyl)methanesulfonyl Chloride

C7H5ClF2O2S

结构：Cl.Cl.O=C(CN1CCNCC1)c1ccccc1
HCID23080512

1-Phenyl-2-(piperazin-1-yl)ethan-1-one--hydrogen chloride (1/2)

C12H18Cl2N2O

PRODUCTS

生成物

1
结构：Cl.O=C(CN1CCN(S(=O)(=O)Cc2ccc(F)cc2F)CC1)c1ccccc1
HCID131726749

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

A mixture of 2,4-difluorobenzylsulfonylchloride (3.5 mmol), N-phenacyl piperazine dihydrochloride (3 mmol), and K2CO3 (10.5 mmol) in 30 ml of DMF was treated according to the general preparation 2 to give compound (IV-22), 0.81 g (71%), M+ 412.

WORKUP

后处理

  1. additionwas treated
  2. customaccording to the general preparation 2
  3. customto give compound (IV-22), 0.81 g (71%), M+ 412