Sodium Chloride → HCID 11434990, compound

HRID 2054723Notes

Reaction equation

HRID 2054723 reaction equation
[C:1]([OH:8])(=O)/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[CH3:6].ClC(OCC)=O.[CH2:15]([N:17](CC)CC)[CH3:16].C(N)C.[Cl-].[Na+]>C1COCC1>[CH2:15]([NH:17][C:1](=[O:8])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[CH3:6])[CH3:16]

Participants

7

Reactant 5

HCID 5234Sodium ChlorideHCID 6341EthylamineHCID 8471TriethylamineHCID 10928Ethyl chloroformateHCID 643460Sorbic Acid

Product 1

HCID 11434990HCID 11434990, compoundYield 26%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

2E,4E-Hexadienoic acid 1 eq, ethyl chloroformate 1.12 eq, triethylamine 1.2 eq, ethylamine 1.5 eq as a 2.0M solution in THF, quench with 10% sodium chloride solution, yield=26%. 1.16 ppm (t, 3H, J=7.27 Hz), 1.82 ppm (d, 3H, J=6.09 Hz), 3.36 ppm (q, 2H, J=7.26 Hz, of d, J=5.73 Hz), 5.77 ppm (d, 1H, J=14.96 Hz), 5.93 ppm (br. s, 1H), 6.01-6.18 ppm (m, 2H), 7.19 ppm (d, 1H, J=14.94 Hz, oft, J=10.14 Hz).

Sources & evidence

ORD record
ord-eb654ba4e4974f75b9c36e30115942f8
Source dataset
uspto-grants-2008_02
Patent number
US07329767B2

Reaction notes

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