Cyclohexanecarboxaldehyde → HCID 178520439, compound

HRID 2059435Notes

Reaction equation

HRID 2059435 reaction equation
O=CC1CCCCC1.O=C(O)CC(=O)N(Cc1ccccc1)Cc1ccccc1>C1CCNCC1.CN(C)c1ccncc1.C1CCOC1>O=C(/C=C/C1CCCCC1)N(Cc1ccccc1)Cc1ccccc1

Participants

6

Reactant 2

HCID 16275CyclohexanecarboxaldehydeHCID 62231246HCID 62231246, compound

Product 1

HCID 178520439HCID 178520439, compoundYield 64%

Reagents, catalysts & solvents 3

HCID 142844-(Dimethylamino)pyridineReagentHCID 8082PiperidineCatalystHCID 8028TetrahydrofuranSolvent

Conditions

Temperature
25 °C

Workup

  1. temperatureThe product mixture was cooled to 25 °C.
  2. filtrationFiltered through a pad of celite · Keep Organic
  3. wash"The celite was washed with ethyl acetate (3 x 1 mL)."
  4. concentrationThe filtrate was concentrated under reduced pressure
  5. additionA 0.07 M stock solution of the internal standard ethylene carbonate (0.70 mL in CDCl3) was added.

Sources & evidence

ORD record
ord-ec13b089023c40319bb70f08c57517c2
Source dataset
Transfer learning optimization of 26 decarboxylative olefination reactions

Reaction notes

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