Hydrochloric Acid → N-Benzyloxy-N-{3-butyl-1-[N'-(4-trifluoromethyl-pyrimidin-2-yl)-hydrazinocarbonyl]-cyclobutylmethyl}-formamide

HRID 206054Notes

Reaction equation

HRID 206054 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][N:9]([CH:10]=[O:11])[CH2:12][C:13]1([C:21](=[O:22])[OH:23])[CH2:14][CH:15]([CH2:17][CH2:18][CH2:19][CH3:20])[CH2:16]1.[CH3:47][N:48]([CH3:49])[CH2:50][CH2:51][CH2:52][N:53]=[C:54]=[N:55][CH2:56][CH3:57].[ClH:46].[NH:24]([NH2:25])[c:26]1[n:27][cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[n:31]1.[O:58]=[CH:59][N:60]([CH3:61])[CH3:62].[OH:36][n:37]1[c:38]2[n:39][cH:40][cH:41][cH:42][c:43]2[n:44][n:45]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][N:9]([CH:10]=[O:11])[CH2:12][C:13]1([C:21](=[O:23])[NH:25][NH:24][c:26]2[n:27][cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[n:31]2)[CH2:14][CH:15]([CH2:17][CH2:18][CH2:19][CH3:20])[CH2:16]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 181649HOAtHCID 12680792-Hydrazino-4-(trifluoromethyl)pyrimidineHCID 86606490(1-[(Benzyloxy-formyl-amino)-methyl)]-3-butyl-cyclobutanecarboxylic acid

Product 1

HCID 86606489N-Benzyloxy-N-{3-butyl-1-[N'-(4-trifluoromethyl-pyrimidin-2-yl)-hydrazinocarbonyl]-cyclobutylmethyl}-formamide

Sources & evidence

ORD record
ord-85d202915033406787b941a20c6e63ee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…