反应详情

2 M hydrochloric acid (30 ml) was added to a solution of the product from stage 4 (748 mg, 1.50 mmol) in tetrahydrofuran (30 ml) and the mixture was stirred at room temperature for 16 h. The mixture was rendered alkaline with 4 M sodium hydroxide solution and extracted with ethyl acetate (3×35 ml). The combined organic phases were dried with sodium sulfate and concentrated i. vac.

1. extractionextracted with ethyl acetate (3×35 ml)
2. dry with materialThe combined organic phases were dried with sodium sulfate
3. concentrationconcentrated i