Methane → N-benzyl-5-(4-(4-methoxyphenyl)piperazin-1-yl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-amine
Reaction equation
[C:51](=[O:52])([O-:53])[O-:54].[CH2:57]1[O:58][CH2:59][CH2:60][CH2:61]1.[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[CH3:7][O:8][c:9]1[cH:10][cH:11][c:12]([N:15]2[CH2:16][CH2:17][N:18]([c:21]3[c:22]([CH3:35])[c:23]([CH3:34])[c:24]4[c:25]([c:32]3[CH3:33])[CH:26]([OH:31])[C:27]([CH3:29])([CH3:30])[O:28]4)[CH2:19][CH2:20]2)[cH:13][cH:14]1.[CH4:6].[K+:55].[K+:56].[NH2:43][CH2:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1.[S:1]([Cl:2])([Cl:3])(=[O:4])=[O:5]>>[CH3:7][O:8][c:9]1[cH:10][cH:11][c:12]([N:15]2[CH2:16][CH2:17][N:18]([c:21]3[c:22]([CH3:35])[c:23]([CH3:34])[c:24]4[c:25]([c:32]3[CH3:33])[CH:26]([NH:43][CH2:44][c:45]3[cH:46][cH:47][cH:48][cH:49][cH:50]3)[C:27]([CH3:29])([CH3:30])[O:28]4)[CH2:19][CH2:20]2)[cH:13][cH:14]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-5bc0bc1d2f0c4c7fb775b271e7e25d47
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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