(Trifluoromethyl)benzene → 3-(Trifluoromethyl)benzenesulfonyl chloride

HRID 2072025Notes

Reaction equation

[C:1]1([C:7]([F:10])([F:9])[F:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:11][S:12](O)(=[O:14])=[O:13].OS(O)(=O)=O.O=S(=O)=O>>[F:8][C:7]([F:10])([F:9])[C:1]1[CH:6]=[C:5]([S:12]([Cl:11])(=[O:14])=[O:13])[CH:4]=[CH:3][CH:2]=1

Participants

Reactant 3

HCID 7368(Trifluoromethyl)benzene

HCID 24638Chlorosulfonic acid

HCID 24681Fuming sulfuric acid

Product 1

HCID 27332503-(Trifluoromethyl)benzenesulfonyl chloride

Procedure

The m-trifluoromethylbenzenesulfonyl chloride starting material was prepared by reacting benzotrifluoride with chlorosulfonic acid in the presence of oleum (65% SO3), according to the method described in Chemical Abstracts 75, 19942d, (1971); German Offen. No. 1,954,448.

Sources & evidence

ORD record: ord-9cfa81f884a64a6e97d6763b3e278951
Source dataset: uspto-grants-1977_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04049695

Reaction notes

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