1-Methylpyrrolidine → HCID 19704841, compound

HRID 2076145Notes

Reaction equation

HRID 2076145 reaction equation
[F:1][C:2]([F:8])([F:7])[S:3]([OH:6])(=[O:5])=[O:4].[CH3:9][N:10]1[CH2:14][CH2:13][CH2:12][CH2:11]1>C(O)C>[F:1][C:2]([F:8])([F:7])[S:3]([OH:6])(=[O:5])=[O:4].[CH3:9][N:10]1[CH2:14][CH2:13][CH2:12][CH2:11]1

Participants

4

Reactant 2

HCID 84541-MethylpyrrolidineHCID 62406Trifluoromethanesulfonic acid

Product 1

HCID 19704841HCID 19704841, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Twenty-five grams of trifluoromethanesulfonic acid was added dropwise to a solution of 14.2 g of 1-methylpyrrolidine in 25 ml of ethanol at 0° C. The solution was returned to room temperature, stirred overnight, and dried in vacuo at 60° C. for 16 hours to furnish 1-methylpyrrolidine trifluoromethanesulfonate (MePy+TfS−) as a brown solid. The resulting salt had a melting point of 97.5° C.

Workup

  1. customwas returned to room temperature
  2. customdried in vacuo at 60° C. for 16 hours

Sources & evidence

ORD record
ord-09c37497228b44c8ad546af9cedcd37d
Source dataset
uspto-grants-2011_04
Patent number
US07923492B2

Reaction notes

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