Hydrochloric Acid → 1-[2-(5-{1-[4-(cyclopropylsulfonyl)phenyl]-2-(tetrahydro-2H-pyran-4-yl)ethyl}-1H-pyrrol-2-yl)-1,3-thiazol-5-yl]ethane-1,2-diol

HRID 207723Notes

Reaction equation

HRID 207723 reaction equation
[CH3:44][CH2:45][O:46][C:47](=[O:48])[CH3:49].[CH:1]1([S:4](=[O:5])(=[O:6])[c:7]2[cH:8][cH:9][c:10]([CH:13]([CH2:14][CH:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[c:21]3[cH:22][cH:23][c:24](-[c:26]4[s:27][c:28]([CH:31]5[O:32][C:33]([CH3:36])([CH3:37])[O:34][CH2:35]5)[cH:29][n:30]4)[nH:25]3)[cH:11][cH:12]2)[CH2:2][CH2:3]1.[ClH:38].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[CH:1]1([S:4](=[O:5])(=[O:6])[c:7]2[cH:8][cH:9][c:10]([CH:13]([CH2:14][CH:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[c:21]3[cH:22][cH:23][c:24](-[c:26]4[s:27][c:28]([CH:31]([OH:32])[CH2:35][OH:34])[cH:29][n:30]4)[nH:25]3)[cH:11][cH:12]2)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 593315412-(5-{1-[4-(cyclopropylsulfonyl)phenyl]-2-(tetrahydro-2H-pyran-4-yl)ethyl}-1H-pyrrol-2-yl)-5-(2,2-dimethyl-1,3-dioxolan-4-yl)-1,3-thiazole

Product 1

HCID 251071661-[2-(5-{1-[4-(cyclopropylsulfonyl)phenyl]-2-(tetrahydro-2H-pyran-4-yl)ethyl}-1H-pyrrol-2-yl)-1,3-thiazol-5-yl]ethane-1,2-diol

Sources & evidence

ORD record
ord-f768d48bd1cb4f4e84fc90640ab487ae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…