HRID2079656

反应详情

EQUATION

反应方程式

HRID 2079656 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

CONDITIONS

反应条件

温度
90 °C

PROCEDURE

实验过程

To a solution of isolated 2,5-dichloroquinazolin-8-ol (1 eq) in isopropanol was added 4-morpholinoaniline (1 eq) and the mixture was heated to 90° C. for 1 h. The SNAR went to completion by LC/MS and on concentration yielded 5-chloro-2-(4-morpholinophenylamino) quinazolin-8-ol in quantitative yield. ES/MS m/z 357 (MH+).

WORKUP

后处理

  1. concentrationThe SNAR went to completion by LC/MS and on concentration