Dimethylformamide → 6-chloro-2,4-dimethyl-N-(3-{4-[(thiazol-4-ylmethyl)-amino]-piperidin-1-yl}-butyl)-nicotinamide
Reaction equation
[CH3:19][CH2:20][N:21]=[C:22]=[N:23][CH2:24][CH2:25][CH2:26][N:27]([CH3:28])[CH3:29].[CH:52]([N:53]([CH2:54][CH3:55])[CH:56]([CH3:57])[CH3:58])([CH3:59])[CH3:60].[Cl:40][c:41]1[n:42][c:43]([CH3:51])[c:44]([C:45](=[O:46])[OH:47])[c:48]([CH3:50])[cH:49]1.[NH2:1][CH2:2][CH2:3][CH:4]([CH3:5])[N:6]1[CH2:7][CH2:8][CH:9]([NH:12][CH2:13][c:14]2[n:15][cH:16][s:17][cH:18]2)[CH2:10][CH2:11]1.[O:61]=[CH:62][N:63]([CH3:64])[CH3:65].[OH:30][n:31]1[c:32]2[c:33]([cH:34][cH:35][cH:36][cH:37]2)[n:38][n:39]1>>[NH:1]([CH2:2][CH2:3][CH:4]([CH3:5])[N:6]1[CH2:7][CH2:8][CH:9]([NH:12][CH2:13][c:14]2[n:15][cH:16][s:17][cH:18]2)[CH2:10][CH2:11]1)[C:45]([c:44]1[c:43]([CH3:51])[n:42][c:41]([Cl:40])[cH:49][c:48]1[CH3:50])=[O:46]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-973fadd7b5c44b79a62d90c41e8f336d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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