Hydrochloric Acid → HCID 20300399, compound

HRID 2083624Notes

Reaction equation

HRID 2083624 reaction equation
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].[CH2:11]([CH:13]([NH2:16])[CH2:14][CH3:15])[CH3:12].Cl>O>[CH2:11]([CH:13]([NH:16][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9])[CH2:14][CH3:15])[CH3:12]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 69451-Chloro-2-nitrobenzeneHCID 120193-Pentanamine

Product 1

HCID 20300399HCID 20300399, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 158 g. of 1-chloro-2-nitrobenzene and 260 g. of 1-ethyl propylamine are refluxed together for 5 days. The solution is cooled and 500 ml. of water is added followed by 10 ml. of concentrated hydrochloric acid. The product separates out as an oil and is extracted with chloroform (2 × 200 ml.). The chloroform layer is dried over MgSO4 and evaporated to yield 190 g. (91%) of product.

Workup

  1. temperatureThe solution is cooled
  2. extractionis extracted with chloroform (2 × 200 ml.)
  3. dry with materialThe chloroform layer is dried over MgSO4
  4. customevaporated
  5. customto yield 190 g

Sources & evidence

ORD record
ord-4e2680c1c5964fb8ae04d79ca108e606
Source dataset
uspto-grants-1978_04
Patent number
US04086242

Reaction notes

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