Methylamine → HCID 68790005, compound

HRID 2085216Notes

Reaction equation

HRID 2085216 reaction equation
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][CH:14]=[CH:13][C:4]=1[CH:5]=[C:6]1[C:10](=O)[O:9][C:8]([CH3:12])=[N:7]1.[CH3:17][NH2:18].C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH3:12][C:8]1[N:18]([CH3:17])[C:10](=[O:9])[C:6](=[CH:5][C:4]2[CH:13]=[CH:14][CH:15]=[CH:16][C:3]=2[O:2][CH3:1])[N:7]=1

Participants

5

Reactant 3

HCID 6329MethylamineHCID 11430Potassium CarbonateHCID 361416HCID 361416, compound

Product 1

HCID 68790005HCID 68790005, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
80 °C

Procedure

4-(2′-Methoxybenzylidene)-2-methyl-4H-oxazol-5-one (5 g) was dissolved in ethanol (100 ml) and aqueous methylamine solution (20 ml) and potassium carbonate (7 g) were added. The mixture was heated at 80° C. for 7 hr. After cooling, the solvent was evaporated under reduced pressure and the precipitated yellow crystals were collected by filtration to give the title compound (2 g).

Workup

  1. temperatureAfter cooling
  2. customthe solvent was evaporated under reduced pressure
  3. filtrationthe precipitated yellow crystals were collected by filtration

Sources & evidence

ORD record
ord-8b0de6a036e443d3a5093007010d941d
Source dataset
uspto-grants-2004_04
Patent number
US06720320B2

Reaction notes

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