反应详情

11.0 g of (±) 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole was dissolved in 180 mL of hot isopropanol and 3.8 mL of methanesulfonic acid was added. The formed precipitate was filtered off after cooling and dried to give 10.2 g of crystals with m.p. 227-237° C.

1. filtrationThe formed precipitate was filtered off
2. temperatureafter cooling
3. customdried