4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine → HCID 22726019, compound

HRID 2087085Notes

Reaction equation

HRID 2087085 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[CH2:10][CH:9]([NH:11][CH2:12][CH2:13][CH3:14])[CH2:8][CH2:7][C:5]=2[N:6]=1.[CH3:15][S:16]([OH:19])(=[O:18])=[O:17]>C(O)(C)C>[CH3:15][S:16]([OH:19])(=[O:18])=[O:17].[NH2:1][C:2]1[S:3][C:4]2[CH2:10][CH:9]([NH:11][CH2:12][CH2:13][CH3:14])[CH2:8][CH2:7][C:5]=2[N:6]=1

Participants

4

Reactant 2

HCID 48854,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamineHCID 6395Methanesulfonic Acid

Product 1

HCID 22726019HCID 22726019, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

11.0 g of (±) 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole was dissolved in 180 mL of hot isopropanol and 3.8 mL of methanesulfonic acid was added. The formed precipitate was filtered off after cooling and dried to give 10.2 g of crystals with m.p. 227-237° C.

Workup

  1. filtrationThe formed precipitate was filtered off
  2. temperatureafter cooling
  3. customdried

Sources & evidence

ORD record
ord-4657c2dbe2d447818139b17591215d95
Source dataset
uspto-grants-2004_04
Patent number
US06727367B2

Reaction notes

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