反应详情

In analogy to the procedure described in example 78.4, 2,5-dichloro-N-[1-imino-2-(2-naphthalen-2-yl-ethoxy)-ethyl]-nicotinamide was treated with potassium carbonate in DMF for 3 h at 100° C. to obtain 6-chloro-2-(2-naphthalen-2-yl-ethoxymethyl)-3H-pyrido[2,3-d]pyrimidin-4-one as brown crystals. MS: m/e=366.0 [M+H+].