Tetrahydrothiophene → Phenacyltetrahydrothiophenium bromide

HRID 2102256Notes

Reaction equation

HRID 2102256 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:4].[S:11]1[CH2:15][CH2:14][CH2:13][CH2:12]1>CC(C)=O>[Br-:1].[O:4]=[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:2][S+:11]1[CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

4

Reactant 2

HCID 1127TetrahydrothiopheneHCID 6259Phenacyl bromide

Product 1

HCID 11346720Phenacyltetrahydrothiophenium bromide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

150 Parts of 2-bromoacetophenone was dissolved in 375 parts of acetone, and 66.5 parts of tetrahydrothiophene was added dropwise to the solution obtained. The resultant mixture was stirred at room temperature for 24 hours and the white precipitates were filtrated, washed, and dried to obtain 207.9 parts of 1-(2-oxo-2-phenylethyl)tetrahydrothiophenium bromide in the form of white crystals.

Workup

  1. additionwas added dropwise to the solution
  2. customobtained
  3. customthe white precipitates
  4. filtrationwere filtrated
  5. washwashed
  6. customdried

Sources & evidence

ORD record
ord-bcbf42c613a94d6d80fffa08ca65ec6d
Source dataset
uspto-grants-2009_08
Patent number
US07575850B2

Reaction notes

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