反应详情

温度

120 °C

A mixture of 2,3-dimethyl-1,4-dihydroquinone (5 g) and benzyl bromide (6.2 g) and K2CO3 (10 g) in DMF (50 mL) was stirred at 120° C. for 5 h. The mixture was poured into water and extracted with EtOAc. The EtOAc was washed with water, dried and evaporated. The residue was purified by silica gel column eluting with 10% EtOAc in hexane to give 3.2 g of 4-benzyloxy-2,3-dimethyl-phenol as a pale solid.

1. extractionextracted with EtOAc
2. washThe EtOAc was washed with water
3. customdried
4. customevaporated
5. customThe residue was purified by silica gel column
6. washeluting with 10% EtOAc in hexane