Butyl bromide → HCID 68815496, compound

HRID 2105944Notes

Reaction equation

HRID 2105944 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1.C(=O)([O-])[O-:16].[K+].[K+].Br[CH2:22][CH2:23][CH2:24][CH3:25]>C(#N)C>[CH2:22]([N:12]1[CH2:13][CH2:14][C:9]([C:3]2[CH:4]=[CH:5][CH:6]=[C:7]([Cl:8])[C:2]=2[Cl:1])([OH:16])[CH2:10][CH2:11]1)[CH2:23][CH2:24][CH3:25]

Participants

5

Reactant 3

HCID 8002Butyl bromideHCID 11430Potassium CarbonateHCID 17895683HCID 17895683, compound

Product 1

HCID 68815496HCID 68815496, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Preparation according to Example 2: 4-(2,3-dichlorophenyl)piperidine (0.02 g, 0.081 mmol), acetonitrile (2 ml), potassium carbonate (0.02 g, 0.14 mmol), bromobutane (0.009 ml, 0.082 mmol). MS m/z (relative intensity, 70 eV) 303 (M+, 2), 302 (M+, 4), 260 (65), 258 (bp), 242 (18), 240 (27).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-2296f46551fa419594f17f0880eb300c
Source dataset
uspto-grants-2009_08
Patent number
US07579474B2

Reaction notes

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