Methylamine → HCID 15016282, compound

HRID 2106600Notes

Reaction equation

HRID 2106600 reaction equation
C(O[C:4]([CH:6]([O:8][C:9]1[N:13]=[CH:12][N:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:10]=1)[CH3:7])=[O:5])C.[CH3:20][NH2:21]>CN(C)C=O>[CH3:20][NH:21][C:4]([CH:6]([O:8][C:9]1[N:13]=[CH:12][N:11]([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:10]=1)[CH3:7])=[O:5]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 14268787HCID 14268787, compound

Product 1

HCID 15016282HCID 15016282, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A 2.5 g portion of the compound of Example 1 was combined with 10 ml of 40% aqueous methylamine and 20 ml of dimethylformamide at room temperature, and the mixture was allowed to stand for 2 days. It was then poured into ice-water, and the solid was collected and air-dried to obtain 0.4 g of the desired product, m.p. 134°-135°.

Workup

  1. customthe solid was collected
  2. customair-dried

Sources & evidence

ORD record
ord-a4e33794dd7546f4bdc7c6f8238cc957
Source dataset
uspto-grants-1990_06
Patent number
US04931083

Reaction notes

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