Potassium Iodide → HCID 23047608, compound

HRID 2107271Notes

Reaction equation

HRID 2107271 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[O:11])[C:8]([O-:10])=[O:9])[N:6]=1.[C:12]1([CH:18](Cl)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[CH2:26](N(CC)CC)[CH3:27].[I-].[K+]>CN(C)C=O>[C:12]1([CH:18]([NH:1][C:2]2[S:3][CH:4]=[C:5]([C:7](=[O:11])[C:8]([O:10][CH2:26][CH3:27])=[O:9])[N:6]=2)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

6

Reactant 4

HCID 4875Potassium IodideHCID 7035ChlorodiphenylmethaneHCID 8471TriethylamineHCID 18962805HCID 18962805, compound

Product 1

HCID 23047608HCID 23047608, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Following a procedure similar to that described in Preparation 53, the desired compound was prepared from 10.1 g of 2-aminothiazol-4-ylglyoxylate, 10.0 g of diphenylmethyl chloride, 10 ml of triethylamine, 10 ml of dimethylformamide and 1.0 g of potassium iodide. The resulting product was a yellow powder having the following physical properties.

Workup

  1. customthat described in Preparation 53

Sources & evidence

ORD record
ord-d421fbde0f3b431abf0d1e1671f7d6ac
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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