Dimethylformamide → Benzyl 2-[[4-[4-(cyclopropylcarbamoyl)phenyl]-1,3-thiazol-2-yl]carbamoyl]-1,3-thiazolidine-3-carboxylate

HRID 211701Notes

Reaction equation

HRID 211701 reaction equation
[CH:1]1([NH:4][C:5](=[O:6])[c:7]2[cH:8][cH:9][c:10](-[c:13]3[n:14][c:15]([NH:18][C:19](=[O:20])[CH:21]4[S:22][CH2:23][CH2:24][NH:25]4)[s:16][cH:17]3)[cH:11][cH:12]2)[CH2:2][CH2:3]1.[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[Cl:35][C:36](=[O:37])[O:38][CH2:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[O:46]=[CH:47][N:48]([CH3:49])[CH3:50]>>[CH:1]1([NH:4][C:5](=[O:6])[c:7]2[cH:8][cH:9][c:10](-[c:13]3[n:14][c:15]([NH:18][C:19](=[O:20])[CH:21]4[S:22][CH2:23][CH2:24][N:25]4[C:36](=[O:37])[O:38][CH2:39][c:40]4[cH:41][cH:42][cH:43][cH:44][cH:45]4)[s:16][cH:17]3)[cH:11][cH:12]2)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 10387Benzyl chloroformateHCID 81531DiisopropylethylamineHCID 178521702HCID 178521702, compound

Product 1

HCID 87484751Benzyl 2-[[4-[4-(cyclopropylcarbamoyl)phenyl]-1,3-thiazol-2-yl]carbamoyl]-1,3-thiazolidine-3-carboxylate

Sources & evidence

ORD record
ord-fe9120b6677e49a4ae8330f6de66fdc0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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