Potassium Iodide → HCID 67151031, compound

HRID 2117995Notes

Reaction equation

HRID 2117995 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6](=[O:18])[C:7](=[O:17])[C:8]3[C:13]([C:14]=2[CH:15]=1)=[CH:12][C:11]([OH:16])=[CH:10][CH:9]=3.C(=O)([O-])[O-].[K+].[K+].[I-].[K+].Br[CH2:28][CH:29]1[CH2:31][CH2:30]1>CC(C)=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6](=[O:18])[C:7](=[O:17])[C:8]3[C:13]([C:14]=2[CH:15]=1)=[CH:12][C:11]([O:16][CH2:28][CH:29]1[CH2:31][CH2:30]1)=[CH:10][CH:9]=3

Participants

6

Reactant 4

HCID 4875Potassium IodideHCID 11430Potassium CarbonateHCID 81503BromomethylcyclopropaneHCID 67151152HCID 67151152, compound

Product 1

HCID 67151031HCID 67151031, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of 3-bromo-6-hydroxyphenanthrene-9,10-dione from Step 4 in acetone was treated with excess potassium carbonate, potassium iodide and (bromomethyl)cyclopropane. The mixture was heated at reflux overnight, followed by standard workup to yield 3-bromo-6-(cyclopropylmethoxy)phenanthrene-9,10-dione.

Workup

  1. temperatureThe mixture was heated
  2. temperatureat reflux overnight

Sources & evidence

ORD record
ord-08a4f0dee9374c02b74d5c78c01fd0b9
Source dataset
uspto-grants-2008_10
Patent number
US07442716B2

Reaction notes

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