Stearoyl chloride → HCID 54428008, compound

HRID 2118700Notes

Reaction equation

HRID 2118700 reaction equation
[CH2:1]([NH:13][C@@H:14]1[O:22][C@H:21]([CH2:23][OH:24])[C@@H:19]([OH:20])[C@H:17]([OH:18])[C@H:15]1[OH:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(N(CC)CC)C.[C:32](Cl)(=[O:50])[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH3:49]>C1COCC1>[CH2:1]([N:13]([CH:14]1[O:22][C@H:21]([CH2:23][OH:24])[C@@H:19]([OH:20])[C@H:17]([OH:18])[C@H:15]1[OH:16])[C:32](=[O:50])[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH3:49])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

5

Reactant 3

HCID 8212Stearoyl chlorideHCID 8471TriethylamineHCID 13361730HCID 13361730, compound

Product 1

HCID 54428008HCID 54428008, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

100 g of N-dodecyl-β-D-glucopyranosylamine from Example 4 are dissolved in 765 ml of THF and, in the presence of 32 g of triethylamine, 80 g of stearoyl chloride are added dropwise, with cooling.

Workup

  1. additionare added dropwise
  2. temperaturewith cooling

Sources & evidence

ORD record
ord-d5dd471bb4f84957b1be1e62d0998fec
Source dataset
uspto-grants-1987_07
Patent number
US04680287

Reaction notes

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