Octadecylamine → HCID 13361751, compound

HRID 2118711Notes

Reaction equation

HRID 2118711 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[CH2:13]([NH2:31])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]>C(O)(C)C.O>[CH2:13]([NH:31][CH:2]1[O:10][C@H:9]([CH2:11][OH:12])[C@H:7]([OH:8])[C@H:5]([OH:6])[C@H:3]1[OH:4])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]

Participants

5

Reactant 2

HCID 15793OctadecylamineHCID 3037556(2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 13361751HCID 13361751, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 3776IsopropanolSolvent

Procedure

60 g of D-galactose are suspended in 330 ml of isopropanol and 170 ml of water, and the mixture is heated to 50°. After addition of 90 g of stearylamine, the mixture is stirred until all the amine has gone into solution. On cooling, the glycosylamine crystallizes out. The solid is filtered off with suction, washed consecutively with ethanol and with ether, and dried in vacuo.

Workup

  1. temperatureOn cooling
  2. customthe glycosylamine crystallizes out
  3. filtrationThe solid is filtered off with suction
  4. washwashed consecutively with ethanol and with ether
  5. customdried in vacuo

Sources & evidence

ORD record
ord-280102638a4649a485330602bae45bc0
Source dataset
uspto-grants-1987_07
Patent number
US04680287

Reaction notes

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