Water → HCID 70443965, compound

HRID 2119150Notes

Reaction equation

HRID 2119150 reaction equation
[ClH:1].O[CH:3]1[O:11][C@H:10]([CH2:12][OH:13])[C@@H:8]([OH:9])[C@H:6]([OH:7])[C@H:4]1[NH2:5].O.[CH2:15]([NH2:33])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]>C(O)(C)C>[ClH:1].[CH2:15]([NH:33][CH:3]1[O:11][C@H:10]([CH2:12][OH:13])[C@@H:8]([OH:9])[C@H:6]([OH:7])[C@H:4]1[NH2:5])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]

Participants

5

Reactant 3

HCID 962WaterHCID 15793OctadecylamineHCID 2723635(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochloride

Product 1

HCID 70443965HCID 70443965, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

6.45 g of D-glucosamine hydrochloride were dissolved in 30 ml of isopropanol and 10 ml of water at 60° C. and 12.1 g of stearylamine were added. The resulting clear solution was stirred for a further 10 minutes and then cooled down to room temperature. The product which had crystallised out was filtered off with suction and initially washed with ethanol/water (5:2, v/v), then with ethanol and finally with ether. The residue was dried under high vacuum.

Workup

  1. customThe product which had crystallised out
  2. filtrationwas filtered off with suction
  3. washinitially washed with ethanol/water (5:2
  4. customThe residue was dried under high vacuum

Sources & evidence

ORD record
ord-f5a049354cca41369f0b400bd539dc67
Source dataset
uspto-grants-1987_07
Patent number
US04683222

Reaction notes

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