Potassium Carbonate → HCID 23438624, compound

HRID 2120109Notes

Reaction equation

HRID 2120109 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.C(=O)([O-])[O-].[K+].[K+].C[N:16]1[CH2:20][CH2:19][CH2:18][C:17]1=O>>[N:16]1([C:2]2[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=2)[CH2:20][CH:19]=[CH:18][CH2:17]1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 13387N-methyl-2-pyrrolidoneHCID 693532,5-Dibromopyridine

Product 1

HCID 23438624HCID 23438624, compound

Procedure

In 100 ml of 1-methyl-2-pyrrolidone was dissolved 10 g of 2,5-dibromopyridine which was then added with 3.5 ml of 3-pyrrolidine, along with 8.7 g of potassium carbonate at room temperature, followed by reacting them at 100° C. for 24 hours. After completion of the reaction, the same post-treatment was carried out as in Preparation Example 3 to obtain the title compound. 8 g.

Workup

  1. customat 100° C.
  2. customfor 24 hours
  3. customAfter completion of the reaction
  4. customthe same post-treatment was carried out as in Preparation Example 3

Sources & evidence

ORD record
ord-ced979dd02a145c296b21c82beee50c2
Source dataset
uspto-grants-2004_02
Patent number
US06689779B2

Reaction notes

Loading…