Potassium Carbonate → HCID 23438670, compound

HRID 2120110Notes

Reaction equation

HRID 2120110 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.[N:9]1[NH:10][N:11]=[CH:12][CH:13]=1.C(=O)([O-])[O-].[K+].[K+]>CN1CCCC1=O>[N:9]1([C:2]2[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=2)[CH:13]=[CH:12][N:11]=[N:10]1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 675161H-1,2,3-TriazoleHCID 693532,5-Dibromopyridine

Product 1

HCID 23438670HCID 23438670, compound

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Procedure

In 20 ml of 1-methyl-2-pyrrolidone was dissolved 1.72 g of 2,5-dibromopyridine, followed by the addition of 500 mg of 2H-(1,2,3)-triazole and 3 g of potassium carbonate at room temperature. Reaction was conducted at 100° C. for 24 hours. After completion of the reaction, the same post-treatment as in Preparation Example 3 was carried out to obtain the title compound. 120 mg.

Workup

  1. customReaction
  2. customAfter completion of the reaction
  3. customthe same post-treatment as in Preparation Example 3

Sources & evidence

ORD record
ord-1cee0ae877e8483c893d0e8ec057fb71
Source dataset
uspto-grants-2004_02
Patent number
US06689779B2

Reaction notes

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