Hydrochloric Acid → 6-Chloro-1,2-dihydro-1-methyl-2-(trifluoromethyl)-3-quinoline-carboxylic acid
Reaction equation
[CH3:25][CH2:26][O:27][CH2:28][CH3:29].[CH3:36][OH:37].[Cl:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[N:8]([CH3:12])[CH:7]([C:13]([F:14])([F:15])[F:16])[C:6]([C:17](=[O:18])[O:19][CH2:20][CH3:21])=[CH:5]2.[ClH:24].[Li+:22].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH-:23].[OH2:30]>>[Cl:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[N:8]([CH3:12])[CH:7]([C:13]([F:14])([F:15])[F:16])[C:6]([C:17](=[O:18])[OH:19])=[CH:5]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-b63b68c9a37242bfa9bd73620adc4e7b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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