Tetrahydrofuran → 3-(4-Chloro-5-fluoro-2,3-dihydroindol-1-yl)-1-phenylpyrrolidin-2-one
Reaction equation
[CH2:17]([P:18]([CH2:19][CH2:20][CH2:21][CH3:22])[CH2:23][CH2:24][CH2:25][CH3:26])[CH2:27][CH2:28][CH3:29].[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[Cl:30][c:31]1[c:32]2[c:36]([cH:37][cH:38][c:39]1[F:40])[N:35]([CH:41]([C:42](=[O:43])[NH:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)[CH2:51][CH2:52][OH:53])[CH2:34][CH2:33]2.[N:1]([C:2]([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])=[O:8])=[N:9][C:10]([O:11][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:16]>>[Cl:30][c:31]1[c:32]2[c:36]([cH:37][cH:38][c:39]1[F:40])[N:35]([CH:41]1[C:42](=[O:43])[N:44]([c:45]3[cH:46][cH:47][cH:48][cH:49][cH:50]3)[CH2:52][CH2:51]1)[CH2:34][CH2:33]2Participants
5
Sources & evidence
- ORD record
- ord-ebf7cb7b01cb4ceeb8ec7cec4ed99291
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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