Bromide ion → 1-(Methoxycarbonyl)-2-(2,4,5-trifluorophenyl)piperidine-4-carboxylic acid
Reaction equation
[Br-:25].[C:33]([O:34][CH3:35])([CH3:36])([CH3:37])[CH3:38].[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:39][C:40]#[N:41].[F:1][c:2]1[c:3]([CH:10]2[N:11]([C:20](=[O:21])[O:22][CH3:23])[CH2:12][CH2:13][CH:14]([C:16](=[O:17])[O:18][CH3:19])[CH2:15]2)[cH:4][c:5]([F:9])[c:6]([F:8])[cH:7]1.[Li+:24].[OH2:42]>>[F:1][c:2]1[c:3]([CH:10]2[N:11]([C:20](=[O:21])[O:22][CH3:23])[CH2:12][CH2:13][CH:14]([C:16](=[O:17])[OH:18])[CH2:15]2)[cH:4][c:5]([F:9])[c:6]([F:8])[cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-25f158e4acbf4de3b7bfdcee7479813d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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