Dimethylformamide → HCID 22051064, compound

HRID 2124525Notes

Reaction equation

HRID 2124525 reaction equation
[CH:25]([N:26]([CH2:27][CH3:28])[CH:29]([CH3:30])[CH3:31])([CH3:32])[CH3:33].[F:1][C:2]([F:3])([F:4])[S:5]([O:6][c:7]1[c:8]([Br:22])[c:9](=[O:21])[n:10]([CH2:14][c:15]2[cH:16][n:17][cH:18][cH:19][cH:20]2)[c:11]([CH3:13])[cH:12]1)(=[O:23])=[O:24].[F:34][c:35]1[cH:36][cH:37][c:38]([C:41]#[CH:42])[cH:39][cH:40]1.[O:43]=[CH:44][N:45]([CH3:46])[CH3:47].[Pd:48]([Cl:49])[Cl:50].[c:51]1([P:52]([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[cH:65][cH:66][cH:67][cH:68][cH:69]1.[c:70]1([P:71]([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[cH:84][cH:85][cH:86][cH:87][cH:88]1>>[c:7]1([C:42]#[C:41][c:38]2[cH:37][cH:36][c:35]([F:34])[cH:40][cH:39]2)[c:8]([Br:22])[c:9](=[O:21])[n:10]([CH2:14][c:15]2[cH:16][n:17][cH:18][cH:19][cH:20]2)[c:11]([CH3:13])[cH:12]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 81531DiisopropylethylamineHCID 5226271-Ethynyl-4-fluorobenzeneHCID 21035326HCID 21035326, compound

Product 1

HCID 22051064HCID 22051064, compound

Sources & evidence

ORD record
ord-544c094704e54369b68cf66cb760eb5c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…