Dichloromethane → N-Trifluoroacetyl-7-benzyloxy-8-bromo-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Reaction equation
[Br:21][CH2:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[CH2:29]1[CH2:30][CH2:31][C:32]2=[N:37][CH2:36][CH2:35][CH2:34][N:33]2[CH2:38][CH2:39]1.[CH3:43][CH2:44][O:45][C:46]([CH3:47])=[O:48].[Cl:40][CH2:41][Cl:42].[F:1][C:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:13][c:14]([Br:18])[c:15]([OH:17])[cH:16]2)[CH:10]([CH3:12])[CH2:11]1)([F:19])[F:20]>>[F:1][C:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:13][c:14]([Br:18])[c:15]([O:17][CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[cH:16]2)[CH:10]([CH3:12])[CH2:11]1)([F:19])[F:20]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-75bd41d3591d4c61a730684a4b1652b1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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