Methanol → Tert-butyl 3-(bromomethyl)-4-hydroxypyrrolidine-1-carboxylate

HRID 2128777Notes

Reaction equation

HRID 2128777 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:14][OH:15])[CH:11]([OH:13])[CH2:12]1.[C:35]([Br:36])([Br:37])([Br:38])[Br:39].[CH3:40][OH:41].[CH3:42][N:43]([CH3:44])[C:45](=[O:46])[CH3:47].[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[Cl:48][CH2:49][Cl:50].[c:16]1([P:17]([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:14][Br:36])[CH:11]([OH:13])[CH2:12]1

Participants

8

Reactant 7

HCID 887MethanolHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 11205Carbon tetrabromideHCID 11776TriphenylphosphineHCID 31374DimethylacetamideHCID 23125669HCID 23125669, compound

Product 1

HCID 23125651Tert-butyl 3-(bromomethyl)-4-hydroxypyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-081844711dba4665a92722cc20a749ee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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