Water → 4-[1-Hydroxycyclopent-1-yl-1-(imidazolyl)methyl]benzonitrile

HRID 2129783Notes

Reaction equation

HRID 2129783 reaction equation
[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[CH:15]([N-:16][CH:17]([CH3:18])[CH3:19])([CH3:20])[CH3:21].[Li+:22].[O:23]=[C:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1.[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1.[OH2:29].[nH:1]1[c:2]([CH2:6][c:7]2[cH:8][cH:9][c:10]([C:11]#[N:12])[cH:13][cH:14]2)[n:3][cH:4][cH:5]1>>[nH:1]1[c:2]([CH:6]([c:7]2[cH:8][cH:9][c:10]([C:11]#[N:12])[cH:13][cH:14]2)[C:24]2([OH:23])[CH2:25][CH2:26][CH2:27][CH2:28]2)[n:3][cH:4][cH:5]1

Participants

8

Reactant 7

HCID 962WaterHCID 8028TetrahydrofuranHCID 8452CyclopentanoneHCID 8857Ethyl AcetateHCID 28486Lithium ionHCID 5062348DiisopropylamideHCID 111481024-(1-Imidazolylmethyl)benzonitrile

Product 1

HCID 544681894-[1-Hydroxycyclopent-1-yl-1-(imidazolyl)methyl]benzonitrile

Sources & evidence

ORD record
ord-541074c57f6c47f4a6c8368724a97254
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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