Tetrahydrofuran → 6-Chloro-3-[(2-fluoro-4-iodophenyl)amino]pyridazine-4-carboxylic acid
Reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:22][Si:23]([N-:24][Si:25]([CH3:26])([CH3:27])[CH3:28])([CH3:29])[CH3:30].[CH3:36][CH2:37][O:38][C:39](=[O:40])[CH3:41].[Cl:10][c:11]1[n:12][n:13][c:14]([Cl:20])[cH:15][c:16]1[C:17](=[O:18])[OH:19].[F:1][c:2]1[c:3]([NH2:4])[cH:5][cH:6][c:7]([I:9])[cH:8]1.[Li+:21]>>[F:1][c:2]1[c:3]([NH:4][c:11]2[n:12][n:13][c:14]([Cl:20])[cH:15][c:16]2[C:17](=[O:18])[OH:19])[cH:5][cH:6][c:7]([I:9])[cH:8]1Participants
7
Sources & evidence
- ORD record
- ord-cbbcf0f59f14436bb2b7bd36f98c0a3a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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