Chloride → Methyl 4-(2-cyclopropyl-1-hydroxyethyl)benzoate

HRID 2133167Notes

Reaction equation

HRID 2133167 reaction equation
[CH:15]([Mg+:16])([CH3:17])[CH3:18].[CH:19]1([CH2:22][CH:23]=[O:24])[CH2:20][CH2:21]1.[Cl-:12].[Cl-:14].[I:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[Li+:13].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[c:2]1([CH:23]([CH2:22][CH:19]2[CH2:20][CH2:21]2)[OH:24])[cH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 312Chloride2×HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 69273Methyl 4-iodobenzoateHCID 103078492-CyclopropylacetaldehydeHCID 178461726HCID 178461726, compound

Product 1

HCID 68178576Methyl 4-(2-cyclopropyl-1-hydroxyethyl)benzoate

Sources & evidence

ORD record
ord-1f335b610149448d9afb53f4450442c9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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