Diethyl Oxalate → Ethyl 4-(hydroxyimino)-3-methyl-2-oxo-4-phenylbutanoate

HRID 2133170Notes

Reaction equation

HRID 2133170 reaction equation
[C:32]([C:33]([O:35][CH2:34][CH3:36])=[O:37])(=[O:38])[O:39][CH2:40][CH3:41].[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:14][CH:15]([N-:16][CH:17]([CH3:18])[CH3:19])[CH3:20].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Li+:13].[Li:8][CH2:9][CH2:10][CH2:11][CH3:12].[c:21]1([C:27]([CH2:28][CH3:29])=[N:30][OH:31])[cH:22][cH:23][cH:24][cH:25][cH:26]1>>[c:21]1([C:27]([CH:28]([CH3:29])[C:33]([C:32](=[O:38])[O:39][CH2:40][CH3:41])=[O:35])=[N:30][OH:31])[cH:22][cH:23][cH:24][cH:25][cH:26]1

Participants

8

Reactant 7

HCID 7268Diethyl OxalateHCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 347963HCID 347963, compoundHCID 5062348DiisopropylamideHCID 178418339Butyllithium

Product 1

HCID 86648115Ethyl 4-(hydroxyimino)-3-methyl-2-oxo-4-phenylbutanoate

Sources & evidence

ORD record
ord-2243cd85a8934f8abb9a4965b3644c38
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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