Diisopropylamine → Silane, trimethyl[[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]ethynyl]-

HRID 2134163Notes

Reaction equation

HRID 2134163 reaction equation
[CH3:15][Si:16]([CH3:17])([CH3:18])[C:19]#[CH:20].[CH:21]([NH:22][CH:23]([CH3:24])[CH3:25])([CH3:26])[CH3:27].[Cu:69][I:70].[I:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH:9]2[O:10][CH2:11][CH2:12][CH2:13][CH2:14]2)[cH:6][cH:7]1.[Pd:28]([Cl:29])[Cl:30].[c:31]1([P:32]([c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[cH:45][cH:46][cH:47][cH:48][cH:49]1.[c:50]1([P:51]([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[cH:64][cH:65][cH:66][cH:67][cH:68]1>>[c:2]1([C:20]#[C:19][Si:16]([CH3:15])([CH3:17])[CH3:18])[cH:3][cH:4][c:5]([O:8][CH:9]2[O:10][CH2:11][CH2:12][CH2:13][CH2:14]2)[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 7912DiisopropylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 29168032H-Pyran, tetrahydro-2-(4-iodophenoxy)-

Product 1

HCID 10540306Silane, trimethyl[[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]ethynyl]-

Sources & evidence

ORD record
ord-b648b4f205fb43bcb32965d45b2767ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…