Bromide ion → 2-(2,6-Difluorobenzyl)-1-(methoxycarbonyl)piperidine-4-carboxylic acid
Reaction equation
[Br-:25].[C:33]([O:34][CH3:35])([CH3:36])([CH3:37])[CH3:38].[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:39][C:40]#[N:41].[F:1][c:2]1[c:3]([CH2:4][CH:5]2[N:6]([C:15](=[O:16])[O:17][CH3:18])[CH2:7][CH2:8][CH:9]([C:11](=[O:12])[O:13][CH3:14])[CH2:10]2)[c:19]([F:23])[cH:20][cH:21][cH:22]1.[Li+:24].[OH2:42]>>[F:1][c:2]1[c:3]([CH2:4][CH:5]2[N:6]([C:15](=[O:16])[O:17][CH3:18])[CH2:7][CH2:8][CH:9]([C:11](=[O:12])[OH:13])[CH2:10]2)[c:19]([F:23])[cH:20][cH:21][cH:22]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-7bb89cae40be41e98d92a0cab2786e54
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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