Water → HCID 59323453, compound

HRID 2136115Notes

Reaction equation

HRID 2136115 reaction equation
[C:31](=[O:32])([n:33]1[cH:34][cH:35][n:36][cH:37]1)[n:38]1[cH:39][cH:40][n:41][cH:42]1.[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[F:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([CH2:12][CH2:13][CH2:14][NH2:15])[CH:6]([CH2:16][c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1)[CH2:5]2.[NH2:24][c:25]1[cH:26][cH:27][n:28][cH:29][cH:30]1.[OH2:43]>>[F:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([CH2:12][CH2:13][CH2:14][NH:15][C:31]([NH:24][c:25]1[cH:26][cH:27][n:28][cH:29][cH:30]1)=[O:32])[CH:6]([CH2:16][c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1)[CH2:5]2

Participants

6

Reactant 5

HCID 962WaterHCID 17274-AminopyridineHCID 8028TetrahydrofuranHCID 682631,1'-CarbonyldiimidazoleHCID 593232933-[6-fluoro-3-(4-fluorobenzyl)-3,4-dihydroisoquinolin-2(1H)-yl]propanamine

Product 1

HCID 59323453HCID 59323453, compound

Sources & evidence

ORD record
ord-4e6df1a7f7b4475c8d4de84e8ace0d53
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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