Hydrochloric Acid → 4-Bromo-3-fluoro-N-methoxy-N-methylbenzamide

HRID 2136176Notes

Reaction equation

HRID 2136176 reaction equation
[Br:7][c:8]1[c:9]([F:17])[cH:10][c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16]1.[C:23](=[O:24])([O-:25])[O-:26].[CH2:29]([Cl:30])[Cl:31].[CH3:19][NH:20][O:21][CH3:22].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[ClH:18].[K+:27].[K+:28].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37].[OH2:32]>>[Br:7][c:8]1[c:9]([F:17])[cH:10][c:11]([C:12](=[O:13])[N:20]([CH3:19])[O:21][CH3:22])[cH:15][cH:16]1

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 14232N,O-DimethylhydroxylamineHCID 19660Carbonate IonHCID 65578Oxalyl chlorideHCID 27733414-Bromo-3-fluorobenzoic acid

Product 1

HCID 223138234-Bromo-3-fluoro-N-methoxy-N-methylbenzamide

Sources & evidence

ORD record
ord-35051fc83e3d444f952fab4dcd434296
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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