Tetrahydrofuran → 5-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][cH:10]2.[CH3:11][Si:12]([CH3:13])([CH3:14])[N-:15][Si:16]([CH3:17])([CH3:18])[CH3:19].[CH:21]([CH3:22])([CH3:23])[Si:24]([Cl:25])([CH:26]([CH3:27])[CH3:28])[CH:29]([CH3:30])[CH3:31].[Li+:20].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([Si:24]([CH:21]([CH3:22])[CH3:23])([CH:26]([CH3:27])[CH3:28])[CH:29]([CH3:30])[CH3:31])[cH:9][cH:10]2Participants
6
Sources & evidence
- ORD record
- ord-f24762f78e9c4b15a678e1e7b73ee37a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…