Methanol → 3-(6,7-Dimethoxyquinazolin-4-yloxy)-4-fluoroaniline
Reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:31][OH:32].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[Cl:16][c:17]1[n:18][cH:19][n:20][c:21]2[cH:22][c:23]([O:29][CH3:30])[c:24]([O:27][CH3:28])[cH:25][c:26]12.[Cs+:5].[Cs+:6].[NH2:7][c:8]1[cH:9][cH:10][c:11]([F:15])[c:12]([OH:14])[cH:13]1.[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[NH2:7][c:8]1[cH:9][cH:10][c:11]([F:15])[c:12]([O:14][c:17]2[n:18][cH:19][n:20][c:21]3[cH:22][c:23]([O:29][CH3:30])[c:24]([O:27][CH3:28])[cH:25][c:26]23)[cH:13]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-0ad8d2280b7a4aafbf6fce3be135f4c9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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