Chloride → 1-(4-Fluoro-3-(trifluoromethyl)phenyl)-1-(3-fluoro-5-(trifluoromethyl)phenyl)-2-phenylethanamine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:12])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[CH2:37]([c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1)[Mg+:44].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:13][CH2:14][CH2:15][CH2:16][Li:17].[CH3:31][Si:32]([Cl:33])([CH3:34])[CH3:35].[CH3:51][CH2:52][O:53][CH2:54][CH3:55].[Cl-:36].[ClH:50].[F:18][c:19]1[c:20]([C:27]([F:28])([F:29])[F:30])[cH:21][c:22]([C:23]#[N:24])[cH:25][cH:26]1>>[c:2]1([C:23]([c:22]2[cH:21][c:20]([C:27]([F:28])([F:29])[F:30])[c:19]([F:18])[cH:26][cH:25]2)([NH2:24])[CH2:37][c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:3][c:4]([F:12])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-298820f4bffb4e17836649411b7eac30
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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